THC/CBD, an endocannabinoid system modulator, has demonstrated efficacy in the treatment of Central Neuropathic Pain in patients with Multiple Sclerosis

Abstract

Central neuropathic pain (CNP), pain initiated or caused by a primary lesion or dysfunction of the central nervous system, occurs in ~28% of patients with multiple sclerosis (MS). Delta(9)-Tetrahydrocannabinol/cannabidiol (THC/CBD), an endocannabinoid system modulator, has demonstrated efficacy for up to 4 weeks in randomized controlled trials in the treatment of CNP in patients with MS.

Clinical Trials, Studies and Publications:

Oromucosal delta9-tetrahydrocannabinol/cannabidiol for neuropathic pain associated with multiple sclerosis: an uncontrolled, open-label, 2-year extension trial

Medical Marijuana for Multiple Sclerosis: A Natural Treatment Option

Multiple SclerosisMultiple Sclerosis is an autoimmune disease that affects the central nervous system. It occurs when the myelin sheath, the covering that protects nerve cells, begins to break down. The nerve cells then become inflamed and damaged, causing painful symptoms, and making life extremely difficult for the sufferer.

Multiple sclerosis symptoms range from mild to severe, and can affect the entire body. Vision problems, muscle weakness and spasms, balance and coordination difficulties, and cognitive problems are all symptoms of the illness. These can be painful and debilitating for the sufferer, although with treatment they can be managed. There is currently no cure for the disease.

Clinical Trials, Studies and Publications:

Treatment for multiple sclerosis addresses the symptoms and can include pain management techniques and painkillers. Unfortunately, the long term effects of these can be very dangerous to the patient. Pain management drugs, especially narcotics, can damage the kidneys with prolonged use. They are also toxic in high doses, and patients can become addicted to them.

An alternative treatment for pain and muscle spasms in Multiple Sclerosis is the use of medical Marijuana, or Cannabis. There are numerous forms of medicating besides smoking for benefits. There are also non-psychoactive alternatives, meaning they will not “get you high”. Patients have reported less muscle spasticity and pain when they used Marijuana. They report feeling looseness in muscles for several hours after using medicinal Marijuana as well.

Patients taking medical Marijuana benefit from a reduction of spasticity in their muscles, as well as a reduction in pain and stiffness. The use of medical Marijuana can improve the quality of life for Multiple Sclerosis without further damaging the body.

Patients are fortunate to have a natural, effective alternative to pharmaceuticals in the treatment of Multiple Sclerosis. With medical Marijuana, they can find the relief that they’ve been searching for, with quick, safe results.