Rationale for cannabis-based interventions in the opioid overdose crisis

This paper presents an evidence-based rationale for cannabis-based interventions in the
opioid overdose crisis informed by research on substitution effect, proposing three important windows of
opportunity for cannabis for therapeutic purposes (CTP) to play a role in reducing opioid use and interrupting the
cycle towards opioid use disorder: 1) prior to opioid introduction in the treatment of chronic pain; 2) as an opioid
reduction strategy for those patients already using opioids; and 3) as an adjunct therapy to methadone or
suboxone treatment in order to increase treatment success rates.

Authors: P Lucas

Clinical Trials, Studies and Publications (click to access):

Harm Reduction Journal (2017) 14:58